Discoid Lupus Erythematosus

Discoid lupus erythematosus (DLE) is an autoimmune chronic skin condition. It is more common in women and typically presents between the ages of 20-50. It is more common in darker-skinned patients and smokers.

Discoid lupus is associated with an increased risk of developing systemic lupus erythematosus. However, this risk is below 5%. Rarely the lesions can progress to squamous cell carcinoma (SCC) of the skin.

 

Presentation

The lesions typically occur on the face, scalp and ears. They are photosensitive, meaning they are made worse by exposure to sunlight. They are associated with scarring alopecia (with scarring and hair loss in affected areas) and hyperpigmentation or hypopigmentation.

The appearance of the lesions or plaques are:

  • Inflamed
  • Dry
  • Erythematous (red)
  • Scaling

 

Management

A skin biopsy can be used to confirm the diagnosis. 

Treatment is with

  • Sun protection
  • Topical steroids
  • Intralesional steroid injections
  • Hydroxychloroquine

 

Last updated August 2023

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